Nicotinic Acetylcholine Receptor Dysfunction in Addiction and in Some Neurodegenerative and Neuropsychiatric Diseases

The cholinergic system plays an essential role in brain development, physiology, and pathophysiology. Herein, we review how specific alterations in this system, through genetic mutations or abnormal receptor function, can lead to aberrant neural circuitry that triggers disease. The review focuses on...

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Bibliographic Details
Main Authors: Ana Sofía Vallés, Francisco J. Barrantes
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/16/2051