Quantitative and Qualitative Image Analysis of <i>In Vitro</i> Co-Culture 3D Tumor Spheroid Model by Employing Image-Processing Techniques

Quantitative and Qualitative Image Analysis of <i>In Vitro</i> Co-Culture 3D Tumor Spheroid Model by Employing Image-Processing Techniques

This work proposes a novel region-estimation (RE) algorithm using the quantification of colon-cancer (HCT-8) and fibroblasts (NIH3T3) cells to estimate the densest region of colon-cancer cells in in vitro 3D co-cultured spheroids. Cells were labelled with different cell tracker dyes to track the cel...

Full description

Bibliographic Details
Main Authors: Mukta Sharma, Venkanagouda S. Goudar, Manohar Prasad Koduri, Fan Gang Tseng, Mahua Bhattacharya
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Applied Sciences
Subjects:
distribution patterns
fibroblast cells
HCT-8 colon-cancer cells
nature-inspired techniques
quantification
segmentation
Online Access:https://www.mdpi.com/2076-3417/11/10/4636

Internet

https://www.mdpi.com/2076-3417/11/10/4636

Similar Items