MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models.

The goal of this study was to determine whether MUC1 antibody conjugated with a fluorophore could be used to visualize pancreatic cancer. Anti-MUC1 (CT2) antibody was conjugated with 550 nm or 650 nm fluorophores. Nude mouse were used to make subcutaneous and orthotopic models of pancreatic cancer....

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Bibliographic Details
Main Authors: Jeong Youp Park, Yukihiko Hiroshima, Jin Young Lee, Ali A Maawy, Robert M Hoffman, Michael Bouvet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376872?pdf=render