Distinct Motifs in ATAD5 C-Terminal Domain Modulate PCNA Unloading Process

Proliferating cell nuclear antigen (PCNA) is a DNA clamp that functions in key roles for DNA replication and repair. After the completion of DNA synthesis, PCNA should be unloaded from DNA in a timely way. The ATAD5-RFC-Like Complex (ATAD5-RLC) unloads PCNA from DNA. However, the mechanism of the PC...

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Bibliographic Details
Main Authors: Eunjin Ryu, Na Young Ha, Woojae Jung, Juyeong Yoo, Kyungjae Myung, Sukhyun Kang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/11/1832