Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion

Neurons in the brain have a uniquely polarized structure consisting of multiple dendrites and a single axon generated from a cell body. Interestingly, intracellular mitochondria also show strikingly polarized morphologies along the dendrites and axons: in cortical pyramidal neurons (PNs), dendritic...

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Bibliographic Details
Main Authors: Su Yeon Kim, Klaudia Strucinska, Bertha Osei, Kihoon Han, Seok-Kyu Kwon, Tommy L. Lewis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1042616/full