Multispectral imaging for MicroChip electrophoresis enables point-of-care newborn hemoglobin variant screening

Multispectral imaging for MicroChip electrophoresis enables point-of-care newborn hemoglobin variant screening

Hemoglobin (Hb) disorders affect nearly 7% of the world’s population. Globally, around 400,000 babies are born annually with sickle cell disease (SCD), primarily in sub-Saharan Africa where morbidity and mortality rates are high. Screening, early diagnosis, and monitoring are not widely accessible d...

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Bibliographic Details
Main Authors: Ran An, Yuning Huang, Anne Rocheleau, Alireza Avanaki, Priyaleela Thota, Qiaochu Zhang, Yuncheng Man, Zoe Sekyonda, Catherine I. Segbefia, Yvonne Dei-Adomakoh, Enoch Mensah, Kwaku Ohene-Frempong, Isaac Odame, Amma Owusu-Ansah, Umut A. Gurkan
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Newborn screening
Genetic hemoglobin disorders
Sickle cell disease
Multispectral imaging
Point-of-care diagnostics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022030663

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http://www.sciencedirect.com/science/article/pii/S2405844022030663

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