DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis

DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis

The protein DJ-1 is mutated in rare familial forms of recessive Parkinson's disease and in parkinsonism accompanied by amyotrophic lateral sclerosis symptoms and dementia. DJ-1 is considered a multitasking protein able to confer protection under various conditions of stress. However, the precis...

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Bibliographic Details
Main Authors: Federica De Lazzari, Francesco Agostini, Nicoletta Plotegher, Michele Sandre, Elisa Greggio, Aram Megighian, Luigi Bubacco, Federica Sandrelli, Alexander J. Whitworth, Marco Bisaglia
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Neurobiology of Disease
Subjects:
DJ-1
Mitochondria
Autophagy
Energy balance
Redox homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122003333

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http://www.sciencedirect.com/science/article/pii/S0969996122003333

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