Clinical characteristics and prognostic significance of DNA methylation regulatory gene mutations in acute myeloid leukemia

Clinical characteristics and prognostic significance of DNA methylation regulatory gene mutations in acute myeloid leukemia

Abstract Background DNA methylation is a form of epigenetic modification that regulates gene expression. However, there are limited data on the comprehensive analysis of DNA methylation regulated gene mutations (DMRGM) in acute myeloid leukemia (AML) mainly referring to DNA methyltransferase 3α (DNM...

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Bibliographic Details
Main Authors: Xiaoyan Xu, Hong Wang, Haohao Han, Yifang Yao, Xueqian Li, Jiaqian Qi, Chengsen Cai, Meng Zhou, Yaqiong Tang, Tingting Pan, Ziyan Zhang, Jingyi Yang, Depei Wu, Yue Han
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Clinical Epigenetics
Subjects:
DNMT3A
IDH1
IDH2
TET2
Acute myeloid leukemia
Prognosis
Online Access:https://doi.org/10.1186/s13148-023-01474-0

Internet

https://doi.org/10.1186/s13148-023-01474-0

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