Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity

<p>Abstract</p> <p>Background</p> <p>Autosomal recessive juvenile parkinsonism (AR-JP) is caused by mutations in the <it>parkin </it>gene which encodes an E3 ubiquitin-protein ligase. Parkin is thought to be critical for protecting dopaminergic neurons from...

Full description

Bibliographic Details
Main Authors: Palmiter Richard D, Curtis Wendy R, Perez Francisco A
Format: Article
Language:English
Published: BMC 2005-12-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/6/71