Functional Brachyury binding sites establish a temporal read-out of gene expression in the Ciona notochord.
The appearance of the notochord represented a milestone in Deuterostome evolution. The notochord is necessary for the development of the chordate body plan and for the formation of the vertebral column and numerous organs. It is known that the transcription factor Brachyury is required for notochord...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-10-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3812116?pdf=render |