Single fraction ablative preoperative radiation treatment for early-stage breast cancer: the CRYSTAL study – a phase I/II clinical trial protocol

Abstract Background Breast-conserving surgery (BCS) and whole breast radiation therapy (WBRT) are the standard of care for early-stage breast cancer (BC). Based on the observation that most local recurrences occurred near the tumor bed, accelerated partial breast irradiation (APBI), consisting of a...

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Main Authors: Maria Alessia Zerella, Mattia Zaffaroni, Giuseppe Ronci, Samantha Dicuonzo, Damaris Patricia Rojas, Anna Morra, Cristiana Fodor, Elena Rondi, Sabrina Vigorito, Francesca Botta, Marta Cremonesi, Cristina Garibaldi, Silvia Penco, Viviana Enrica Galimberti, Mattia Intra, Sara Gandini, Massimo Barberis, Giuseppe Renne, Federica Cattani, Paolo Veronesi, Roberto Orecchia, Barbara Alicja Jereczek-Fossa, Maria Cristina Leonardi
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09305-w