Apolipoprotein CIII may mediate the impacts of angiopoietin-like protein 8 on triglyceride metabolism

Abstract Background Angiopoietin-like protein 8(ANGPTL8) and apolipoprotein CIII (apoCIII) were found to inhibit the activity of lipoprotein lipase (LPL) and disrupt the clearance of triglyceride-rich lipoproteins (TRLs), leading to hypertriglyceridemia. Whether any relationship exists between these...

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Bibliographic Details
Main Authors: Mengdie Luo, Xin Su, Yuhong Yi, Yang Yang, Daoquan Peng
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-018-0777-6