Apolipoprotein CIII may mediate the impacts of angiopoietin-like protein 8 on triglyceride metabolism
Abstract Background Angiopoietin-like protein 8(ANGPTL8) and apolipoprotein CIII (apoCIII) were found to inhibit the activity of lipoprotein lipase (LPL) and disrupt the clearance of triglyceride-rich lipoproteins (TRLs), leading to hypertriglyceridemia. Whether any relationship exists between these...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | Lipids in Health and Disease |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12944-018-0777-6 |