Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction.

Microvascular injury (MVI) after coronary ischemia-reperfusion is associated with high morbidity and mortality. Both ischemia and reperfusion are involved in MVI, but to what degree these phases contribute is unknown. Understanding the etiology is essential for the development of new potential thera...

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Main Authors: Maurits R Hollander, Guus A de Waard, Lara S F Konijnenberg, Rosalie M E Meijer-van Putten, Charissa E van den Brom, Nanne Paauw, Helga E de Vries, Peter M van de Ven, Jurjan Aman, Geerten P Van Nieuw-Amerongen, Peter L Hordijk, Hans W M Niessen, Anton J G Horrevoets, Niels Van Royen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4938574?pdf=render