A novel small molecule glycolysis inhibitor WZ35 exerts anti-cancer effect via metabolic reprogramming

A novel small molecule glycolysis inhibitor WZ35 exerts anti-cancer effect via metabolic reprogramming

Abstract Background Liver cancer is the fifth leading cause of cancer death worldwide, but early diagnosis and treatment of liver cancer remains a clinical challenge. How to screen and diagnose liver cancer early and prolong the survival rate is still the focus of researchers. Methods Cell experimen...

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Bibliographic Details
Main Authors: Lihua Wang, Zheng Zhu, Qi Liang, Yecheng Tao, Gaowei Jin, Yaoyao Zhong, Jichen Dai, Ruixia Dai, Zhixiang Wang, Junbo Chen, Lingjie Zhou, Shouyu Ke, Bin Zheng, Linhua Lan, Xiaokun Lin, Tongke Chen
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Hepatocellular carcinoma
WZ35
Metabolic reprogramming
GLUT1
YAP
Online Access:https://doi.org/10.1186/s12967-022-03758-0

Internet

https://doi.org/10.1186/s12967-022-03758-0

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