Potential of fluoropyrimidine to be an immunologically optimal partner of immune checkpoint inhibitors through inducing immunogenic cell death for thoracic malignancies

Potential of fluoropyrimidine to be an immunologically optimal partner of immune checkpoint inhibitors through inducing immunogenic cell death for thoracic malignancies

Abstract Background Immune checkpoint inhibitors (ICIs) are a revolutionary paradigm in the treatment of thoracic malignancies and chemoimmunotherapy is a current standard care in this field. Chemotherapeutic agents are known to induce not only direct cytotoxic effects on tumor cells but also immune...

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Bibliographic Details
Main Authors: Hiroyuki Kozai, Hirokazu Ogino, Atsushi Mitsuhashi, Na Thi Nguyen, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Hiroto Yoneda, Seidai Sato, Masaki Hanibuchi, Tsutomu Shinohara, Hiroshi Nokihara, Yasuhiko Nishioka
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Thoracic Cancer
Subjects:
5‐fluorouracil
cancer immunotherapy
fluoropyrimidine
immunogenic cell death
thoracic malignancy
Online Access:https://doi.org/10.1111/1759-7714.15200

Internet

https://doi.org/10.1111/1759-7714.15200

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