Antimicrobial Activity of Nitrogen-Containing 5-α-Androstane Derivatives: In Silico and Experimental Studies

Antimicrobial Activity of Nitrogen-Containing 5-α-Androstane Derivatives: In Silico and Experimental Studies

We evaluated the antimicrobial activity of thirty-one nitrogen-containing 5-α-androstane derivatives in silico using computer program PASS (Prediction of Activity Spectra for Substances) and freely available PASS-based web applications (such as Way2Drug). Antibacterial activity was predicted for 27...

Full description

Bibliographic Details
Main Authors: Lela Amiranashvili, Nanuli Nadaraia, Maia Merlani, Charalampos Kamoutsis, Anthi Petrou, Athina Geronikaki, Pavel Pogodin, Dmitry Druzhilovskiy, Vladimir Poroikov, Ana Ciric, Jasmina Glamočlija, Marina Sokovic
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Antibiotics
Subjects:
antibacterial activity
antifungal activity
potency against the resistant strains
PASS
GUSAR
CLC-Pred
Online Access:https://www.mdpi.com/2079-6382/9/5/224

Internet

https://www.mdpi.com/2079-6382/9/5/224

Similar Items