ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cells.

Lung cancer is the leading cause of cancer death worldwide, and brain metastasis is a major cause of morbidity and mortality in lung cancer. CDH2 (N-cadherin, a mesenchymal marker of the epithelial-mesenchymal transition) and ADAM9 (a type I transmembrane protein) are related to lung cancer brain me...

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Bibliographic Details
Main Authors: Yuh-Pyng Sher, Li-Ju Wang, Li-Ling Chuang, Mong-Hsun Tsai, Ting-Ting Kuo, Cheng-Chung Huang, Eric Y Chuang, Liang-Chuan Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3976390?pdf=render