PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.

PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.

<h4>Background</h4>PNPLA3 rs738409 minor allele c.444G represents a risk factor for liver steatosis and fibrosis progression also in chronic hepatitis C (HCV). We investigated its impact on the timing of liver transplantation (LT) in patients with genotype 1b HCV cirrhosis.<h4>Meth...

Full description

Bibliographic Details
Main Authors: Renata Senkerikova, Sona Frankova, Milan Jirsa, Miluse Kreidlova, Dusan Merta, Magdalena Neroldova, Klara Chmelova, Julius Spicak, Jan Sperl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222609

Internet

https://doi.org/10.1371/journal.pone.0222609

Similar Items