Ginsenoside Rp1, A Ginsenoside Derivative, Augments Anti-Cancer Effects of Actinomycin D via Downregulation of an AKT-SIRT1 Pathway

Ginsenoside Rp1, A Ginsenoside Derivative, Augments Anti-Cancer Effects of Actinomycin D via Downregulation of an AKT-SIRT1 Pathway

Novel strategies for overcoming multidrug resistance are urgently needed to improve chemotherapy success and reduce side effects. Ginsenosides, the main active components of <i>Panax ginseng</i>, display anti-cancer properties and reverse drug resistance; however, the biological pathways...

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Bibliographic Details
Main Authors: Un-Jung Yun, In Hye Lee, Jae-Seon Lee, Jaegal Shim, Yong-Nyun Kim
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
actinomycin d
akt
combination therapy
colon cancer
ginsenoside rp1
multidrug resistance
sirt1
Online Access:https://www.mdpi.com/2072-6694/12/3/605

Internet

https://www.mdpi.com/2072-6694/12/3/605

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