Cell-based <i>in vitro</i> hemoassay for evaluation of NLRP3-inflammasome activity

Cell-based <i>in vitro</i> hemoassay for evaluation of NLRP3-inflammasome activity

Currently, gouty arthritis is considered as a polygenic multifactorial autoinflammatory disease caused by activation of the NOD (nucleotide-binding domain) -like protein receptor 3 inflammasome NLRP3. The two cytokines IL-1β and IL-18 are considered important biomarkers of NLRP3 inflammasome activat...

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Bibliographic Details
Main Authors: N. K. Ossina, L. T. Volova, P. A. Lebedev, I. A. Shafieva, E. I. Pugachev, S. A. Goncharenko, S. I. Kuznetsov, O. A. Gusyakova, G. N. Svetlova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2024-09-01
Series:Медицинская иммунология
Subjects:
cell-based assay
il-18
inflammasome nlrp3
gouty arthritis
serum
uric acid
cytokines
Online Access:https://www.mimmun.ru/mimmun/article/view/3087

Internet

https://www.mimmun.ru/mimmun/article/view/3087

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