Rapid restructurization of conformationally-distinct alpha-synuclein amyloid fibrils at an elevated temperature

Protein aggregation in the form of amyloid fibrils is linked with the onset and progression of more than 30 amyloidoses, including multiple neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease. Despite countless studies and years of research, the process of such aggregate formatio...

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Bibliographic Details
Main Authors: Mantas Ziaunys, Andrius Sakalauskas, Kamile Mikalauskaite, Vytautas Smirnovas
Format: Article
Language:English
Published: PeerJ Inc. 2022-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14137.pdf