Icariin stimulates differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs) through activation of cAMP/PKA/CREB

Icariin, a prenylated flavonol glycoside isolated from Epimedium, has been considered as a potential alternative therapy for osteoporosis. The present study aimed to clarify the detailed molecular mechanisms of action of icariin on osteoblast function, using bone marrow-derived mesenchymal stem cell...

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Bibliographic Details
Main Authors: Dan Lou, Jifeng Ye, Lianhua Yang, Zheng Wu, Wei Zheng, Hui Zhang
Format: Article
Language:English
Published: Universidade de São Paulo 2019-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100592&tlng=en