Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation.

Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation.

<h4>Background</h4>Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular oxygen consumption rate (OCR) i...

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Bibliographic Details
Main Authors: Klearchos K Papas, Melena D Bellin, David E R Sutherland, Thomas M Suszynski, Jennifer P Kitzmann, Efstathios S Avgoustiniatos, Angelika C Gruessner, Kathryn R Mueller, Gregory J Beilman, Appakalai N Balamurugan, Gopalakrishnan Loganathan, Clark K Colton, Maria Koulmanda, Gordon C Weir, Josh J Wilhelm, Dajun Qian, Joyce C Niland, Bernhard J Hering
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0134428

Internet

https://doi.org/10.1371/journal.pone.0134428

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