Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients

Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients

Abstract Background Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are frequent and serious complications after surgery. We aim to investigate the association between genetic variants in cholinergic candidate genes according to the Kyoto encyclopedia of genes and genomes...

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Bibliographic Details
Main Authors: Maria Heinrich, Miriam Sieg, Jochen Kruppa, Peter Nürnberg, Peter H. Schreier, Stefanie Heilmann-Heimbach, Per Hoffmann, Markus M. Nöthen, Jürgen Janke, Tobias Pischon, Arjen J. C. Slooter, Georg Winterer, Claudia D. Spies
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Medical Genomics
Subjects:
CHRM2
CHRM4
Genome-wide association study
Neurocognitive disorder
Online Access:https://doi.org/10.1186/s12920-021-01071-1

Internet

https://doi.org/10.1186/s12920-021-01071-1

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