Proteome analysis for downstream targets of oncogenic KRAS--the potential participation of CLIC4 in carcinogenesis in the lung.

Proteome analysis for downstream targets of oncogenic KRAS--the potential participation of CLIC4 in carcinogenesis in the lung.

This study investigated the proteome modulated by oncogenic KRAS in immortalized airway epithelial cells. Chloride intracellular channel protein 4 (CLIC4), S100 proteins (S100A2 and S100A11), tropomyosin 2, cathepsin L1, integrinsα3, eukaryotic elongation factor 1, vimentin, and others were discrimi...

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Bibliographic Details
Main Authors: Koji Okudela, Akira Katayama, Tetsukan Woo, Hideaki Mitsui, Takehisa Suzuki, Yoko Tateishi, Shigeaki Umeda, Michihiko Tajiri, Munetaka Masuda, Noriyuki Nagahara, Hitoshi Kitamura, Kenichi Ohashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913595?pdf=render

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http://europepmc.org/articles/PMC3913595?pdf=render

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