3D printing technique applied in vaginoplasty: A case report

Background: We present the first case report of the treatment of congenital vaginal atresia by 3D-printed patient-specific vaginal scaffold from China. Case presentation: A 17-year-old female patient was referred to our department for treatment of congenital vaginal atresia and complications arising...

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Main Authors: Guo-wu Yin, Tao Han, Jia-he Liang, Jiang-pu Yi, Jing-jing Wang, Zhao-wei Gao, Jing-chun Ren, Qian Fu, Yun Li, Ling-li Jin, Rong Fei, Tie-sheng Cao, Xiao-ming Zhu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022031565
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author Guo-wu Yin
Tao Han
Jia-he Liang
Jiang-pu Yi
Jing-jing Wang
Zhao-wei Gao
Jing-chun Ren
Qian Fu
Yun Li
Ling-li Jin
Rong Fei
Tie-sheng Cao
Xiao-ming Zhu
author_facet Guo-wu Yin
Tao Han
Jia-he Liang
Jiang-pu Yi
Jing-jing Wang
Zhao-wei Gao
Jing-chun Ren
Qian Fu
Yun Li
Ling-li Jin
Rong Fei
Tie-sheng Cao
Xiao-ming Zhu
author_sort Guo-wu Yin
collection DOAJ
description Background: We present the first case report of the treatment of congenital vaginal atresia by 3D-printed patient-specific vaginal scaffold from China. Case presentation: A 17-year-old female patient was referred to our department for treatment of congenital vaginal atresia and complications arising from previous failed operations. Pelvic examination was conducted to understand the morphological characteristics and severity of stenosis, and based on which we designed our prototypes of vaginal scaffold using software UG NX10.0. We finally obtained our patient-specific mold, which was 50 mm in length, 28 mm in diameter, 2 mm of thickness with a whole weight of 7.6 g, and it was made of polycaprolactone. After removing scar tissues caused by vaginal stenosis, an 8 cm long artificial tunnel was created, and then the polycaprolactone (PCL) vaginal mold was placed and sutured. The patient had no discomfort after surgery and was discharged 3 days after the surgery. Follow-up for 1 year after surgery, through hysteroscopy and colposcopy, it was found that the cervix was smooth, the vaginal wall was covered with stratified squamous epithelium, and the vaginal wall was soft and lubricated, which was close to a normal vagina. The incompletely absorbed mold was taken out one year after the operation. Hysteroscopy and colposcopy were performed one year and two years after the mold was taken out. The vagina was unobstructed and the length was about 12 cm. The appearance of the vaginal wrinkles was normal. The patient's quality of sexual life was good. Conclusion: Our team tried to treat congenital vaginal atresia by 3D-printed patient-specific vaginal scaffold, which can effectively reduce patient complications and reduce patient pain. Through long-term follow-up, we found that this technique has achieved favorable results and improved the patient's quality of sexual life.
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spelling doaj.art-3b1be8c997404ec5b0dca2108853a5542023-01-05T08:37:13ZengElsevierHeliyon2405-84402022-12-01812e118683D printing technique applied in vaginoplasty: A case reportGuo-wu Yin0Tao Han1Jia-he Liang2Jiang-pu Yi3Jing-jing Wang4Zhao-wei Gao5Jing-chun Ren6Qian Fu7Yun Li8Ling-li Jin9Rong Fei10Tie-sheng Cao11Xiao-ming Zhu12Department of Obstetrics and Gynecology, Qujiang Obstetrics and Gynecology Hospital, Xi'an, ChinaDepartment of Orthopedics, Hainan Branch of PLA General Hospital, Sanya, ChinaDepartment of Ultrasound, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Ultrasound, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Obstetrics and Gynecology, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Clinical Laboratory, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Obstetrics and Gynecology, Qujiang Obstetrics and Gynecology Hospital, Xi'an, ChinaDepartment of Obstetrics and Gynecology, Qujiang Obstetrics and Gynecology Hospital, Xi'an, ChinaDepartment of Obstetrics and Gynecology, Qujiang Obstetrics and Gynecology Hospital, Xi'an, ChinaDepartment of Anesthesiology, Qujiang Obstetrics and Gynecology Hospital, Xi'an, ChinaOperating Room, Qujiang Obstetrics and Gynecology Hospital, Xi'an, ChinaDepartment of Ultrasound, Tangdu Hospital, Air Force Medical University, Xi'an, China; Corresponding author.Department of Obstetrics and Gynecology, Hainan Branch of PLA General Hospital, Sanya, China; Corresponding author.Background: We present the first case report of the treatment of congenital vaginal atresia by 3D-printed patient-specific vaginal scaffold from China. Case presentation: A 17-year-old female patient was referred to our department for treatment of congenital vaginal atresia and complications arising from previous failed operations. Pelvic examination was conducted to understand the morphological characteristics and severity of stenosis, and based on which we designed our prototypes of vaginal scaffold using software UG NX10.0. We finally obtained our patient-specific mold, which was 50 mm in length, 28 mm in diameter, 2 mm of thickness with a whole weight of 7.6 g, and it was made of polycaprolactone. After removing scar tissues caused by vaginal stenosis, an 8 cm long artificial tunnel was created, and then the polycaprolactone (PCL) vaginal mold was placed and sutured. The patient had no discomfort after surgery and was discharged 3 days after the surgery. Follow-up for 1 year after surgery, through hysteroscopy and colposcopy, it was found that the cervix was smooth, the vaginal wall was covered with stratified squamous epithelium, and the vaginal wall was soft and lubricated, which was close to a normal vagina. The incompletely absorbed mold was taken out one year after the operation. Hysteroscopy and colposcopy were performed one year and two years after the mold was taken out. The vagina was unobstructed and the length was about 12 cm. The appearance of the vaginal wrinkles was normal. The patient's quality of sexual life was good. Conclusion: Our team tried to treat congenital vaginal atresia by 3D-printed patient-specific vaginal scaffold, which can effectively reduce patient complications and reduce patient pain. Through long-term follow-up, we found that this technique has achieved favorable results and improved the patient's quality of sexual life.http://www.sciencedirect.com/science/article/pii/S2405844022031565Vaginoplasty3D printingVaginal moldPolycaprolactone
spellingShingle Guo-wu Yin
Tao Han
Jia-he Liang
Jiang-pu Yi
Jing-jing Wang
Zhao-wei Gao
Jing-chun Ren
Qian Fu
Yun Li
Ling-li Jin
Rong Fei
Tie-sheng Cao
Xiao-ming Zhu
3D printing technique applied in vaginoplasty: A case report
Heliyon
Vaginoplasty
3D printing
Vaginal mold
Polycaprolactone
title 3D printing technique applied in vaginoplasty: A case report
title_full 3D printing technique applied in vaginoplasty: A case report
title_fullStr 3D printing technique applied in vaginoplasty: A case report
title_full_unstemmed 3D printing technique applied in vaginoplasty: A case report
title_short 3D printing technique applied in vaginoplasty: A case report
title_sort 3d printing technique applied in vaginoplasty a case report
topic Vaginoplasty
3D printing
Vaginal mold
Polycaprolactone
url http://www.sciencedirect.com/science/article/pii/S2405844022031565
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