Automated quality control tool for high-content imaging data by building 2D prediction intervals on reference biosignatures

Recent advances in automated microscopy and image analysis enables quantitative profiling of cellular phenotypes (Cell Painting). It paves the way for studying the broad effects of chemical perturbations on biological systems at large scale during lead optimization. Comparison of perturbation biosig...

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Bibliographic Details
Main Authors: Alemu Takele Assefa, Bie Verbist, Emmanuel Gustin, Danielle Peeters
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:SLAS Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2472555223000114