Synthesis of Quinolones and Zwitterionic Quinolonate Derivatives with Broad-Spectrum Antibiotic Activity

Quinolones are one of the most extensively used therapeutic families of antibiotics. However, the increase in antibiotic-resistant bacteria has rendered many of the available compounds useless. After applying our prediction model of activity against <i>E. coli</i> to a library of 1000 qu...

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Bibliographic Details
Main Authors: Beatriz Suay-García, Jose-Ignacio Bueso-Bordils, Gerardo Antón-Fos, María-Teresa Pérez-Gracia, Antonio Falcó, Pedro Alemán-López
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/7/818