THROMBOCYTOPENIA CAUSED BY INHERITED HAEMATOPOIETIC TRANSCRIPTION FACTOR MUTATION: CLINICAL PHENOTYPES AND DIAGNOSTIC CONSIDERATIONS

THROMBOCYTOPENIA CAUSED BY INHERITED HAEMATOPOIETIC TRANSCRIPTION FACTOR MUTATION: CLINICAL PHENOTYPES AND DIAGNOSTIC CONSIDERATIONS

Inherited thrombocytopenias comprise a heterogeneous group of blood disorders with abnormalities in genes related to glycoproteins and adhesion molecules, signalling pathways, cytoskeletal components, granule formation, and transcription factor complexes. Recent improvements in sequencing technology...

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Bibliographic Details
Main Authors: David J. Rabbolini, Christopher M. Ward, William S. Stevenson
Format: Article
Language:English
Published: European Medical Journal 2016-07-01
Series:European Medical Journal Hematology
Subjects:
transcription factors
inherited thrombocytopenia
megakaryopoiesis
next-generation sequencing
Online Access:https://www.emjreviews.com/hematology/article/thrombocytopenia-caused-by-inherited-haematopoietic-transcription-factor-mutation-clinical-phenotypes-and-diagnostic-considerations/

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https://www.emjreviews.com/hematology/article/thrombocytopenia-caused-by-inherited-haematopoietic-transcription-factor-mutation-clinical-phenotypes-and-diagnostic-considerations/

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