Skeletal Muscle Na+ Channel Disorders

Skeletal Muscle Na+ Channel Disorders

Five inherited human disorders affecting skeletal muscle contraction have been traced to mutations in the gene encoding the voltage-gated sodium channel Nav1.4. The main symptoms of these disorders are myotonia or periodic paralysis caused by changes in skeletal muscle fiber excitability. Symptoms o...

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Bibliographic Details
Main Authors:	Dina eSimkin, Saïd eBendahhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2011-10-01
Series:	Frontiers in Pharmacology
Subjects:	skeletal muscle Sodium channel Treatment Nav1.4
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00063/full

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