Metabolism and DNA Adduct Formation of Tobacco-Specific <i>N</i>-Nitrosamines

The tobacco-specific <i>N</i>-nitrosamines 4-(<i>N</i>-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) and <i>N</i>′-nitrosonornicotine (NNN) always occur together and exclusively in tobacco products or in environments contaminated by tobacco smoke. They have b...

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Bibliographic Details
Main Authors: Yupeng Li, Stephen S. Hecht
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/9/5109