Adjuvant Trastuzumab in HER2-Positive Early Breast Cancer by Age and Hormone Receptor Status: A Cost-Utility Analysis.

The anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab improves outcomes in patients with node-positive HER2+ early breast cancer. Given trastuzumab's high cost, we aimed to estimate its cost-effectiveness by heterogeneity in age and estrogen receptor (ER) and...

Full description

Bibliographic Details
Main Authors: William Leung, Giorgi Kvizhinadze, Nisha Nair, Tony Blakely
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC4978494?pdf=render