Regioselective ring opening of aziridine for synthesizing azaheterocycle

Aziridine had different regioselective ring openings depending on the functional group of its alkyl substituent. In the case of the alkyl group bearing γ-ketone at the C2 substituent of aziridine, the ring opening by the hydroxy nucleophile from H2O occurred by attacking the aziridine carbon at the...

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Bibliographic Details
Main Authors: Nikhil Srivastava, Hyun-Joon Ha
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1280633/full