Docking protein-1 promotes inflammatory macrophage signaling in gastric cancer

Docking protein-1 promotes inflammatory macrophage signaling in gastric cancer

Docking protein-1 (DOK1) is a tumor suppressor frequently lost in malignant cells, however, it retains the ability to control activities of immune receptors in adjacent stroma cells of the tumor microenvironment. We therefore hypothesized that addressing DOK1 may be useful for cancer immunotherapy....

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Bibliographic Details
Main Authors: Tong Li, Beifang Li, Asgharpour Sara, Christine Ay, Wing Yan Leung, Yanquan Zhang, Yujuan Dong, Qiaoyi Liang, Xiang Zhang, Philip Weidner, Tobias Gutting, Hans-Michael Behrens, Christoph Röcken, Joseph JY Sung, Matthias P. Ebert, Jun Yu, Elke Burgermeister
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:OncoImmunology
Subjects:
gastric cancer
dok1
pd-l1
ppar
macrophage
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1649961

Internet

http://dx.doi.org/10.1080/2162402X.2019.1649961

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