secHsp70 as a tool to approach amyloid-β42 and other extracellular amyloids

Self-association of amyloidogenic proteins is the main pathological trigger in a wide variety of neurodegenerative disorders. These aggregates are deposited inside or outside the cell due to hereditary mutations, environmental exposures or even normal aging. Cumulative evidence indicates that the he...

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Bibliographic Details
Main Authors: Lorena De Mena, Deepak Chhangani, Pedro Fernandez-Funez, Diego E. Rincon-Limas
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Fly
Subjects:
Online Access:http://dx.doi.org/10.1080/19336934.2017.1291104