Vitamin B12 Supplementation Improves Oocyte Development by Modulating Mitochondria and Yolk Protein in a Caffeine-Ingested <i>Caenorhabditis elegans</i> Model

Vitamin B12 is an essential cofactor involved in the function of two enzymes: cytosolic methionine synthase and mitochondrial methylmalonic-CoA mutase. In our previous studies, caffeine (1,3,7-trimethylxanthine), the most popular bioactivator, was shown to reduce yolk protein (vitellogenin) and fert...

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Bibliographic Details
Main Authors: Hyemin Min, Mijin Lee, Sangwon Kang, Yhong-Hee Shim
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/13/1/53