Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent Manner

Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent Manner

ABSTRACT The gut microbiome is involved in metabolic disorders. Osteopontin (OPN), as a key cytokine, contributes to various inflammation-related diseases. The underlying role of OPN in the microbiome remains poorly understood. Here, we investigated whether OPN could modulate metabolic disorders by...

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Bibliographic Details
Main Authors: Jianing Chen, Ping Zeng, Lan Gong, Xujun Zhang, Zongxin Ling, Kefan Bi, Fan Shi, Kaihang Wang, Qiong Zhang, Jingjing Jiang, Yanhui Zhang, Toshimitsu Uede, Emad M. El-Omar, Hongyan Diao
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
osteopontin
high-fat diet
metabolic disorder
gut microbiome
adhesion
Online Access:https://journals.asm.org/doi/10.1128/mbio.02531-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02531-22

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