Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma
Somatic copy-number alterations (SCNAs) are major contributors to cancer development that are pervasive and highly heterogeneous in human cancers. However, the driver roles of SCNAs in cancer are insufficiently characterized. We combined network propagation and linear regression models to design an...
Main Authors: | Yao Zhou, Shuai Wang, Haoteng Yan, Bo Pang, Xinxin Zhang, Lin Pang, Yihan Wang, Jinyuan Xu, Jing Hu, Yujia Lan, Yanyan Ping |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2021.654736/full |
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