Polyinosinic: polycytidylic acid induced inflammation enhances while lipopolysaccharide diminishes alloimmunity to platelet transfusion in mice

Polyinosinic: polycytidylic acid induced inflammation enhances while lipopolysaccharide diminishes alloimmunity to platelet transfusion in mice

IntroductionAlloimmune responses against platelet antigens, which dominantly target the major histocompatibility complex (MHC), can cause adverse reactions to subsequent platelet transfusions, platelet refractoriness, or rejection of future transplants. Platelet transfusion recipients include indivi...

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Bibliographic Details
Main Authors: Johnson Q. Tran, Marcus O. Muench, Betty Gaillard, Orsolya Darst, Mary M. Tomayko, Rachael P. Jackman
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
platelets
alloimmunization
underlying health
inflammation
poly(I:C)
lipopolysaccharide
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1281130/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1281130/full

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