Bactericidal antibodies against hypervirulent Neisseria meningitidis C field strains following MenC-CRM or MenACWY-CRM priming and MenACWY-CRM booster in children

Bactericidal antibodies against hypervirulent Neisseria meningitidis C field strains following MenC-CRM or MenACWY-CRM priming and MenACWY-CRM booster in children

An increase in invasive meningococcal disease (IMD) incidence was observed in Tuscany in 2015/2016, mainly due to hypervirulent clonal complex (cc) 11 strains. In a post-hoc analysis, we assessed bactericidal activity of antibodies in sera from children primed with MenACWY-CRM or MenC-CRM conjugate...

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Bibliographic Details
Main Authors: Marzia Monica Giuliani, Alessia Biolchi, Pavitra Keshavan, Maria Moriondo, Sara Tomei, Laura Santini, Elena Mori, Alessandro Brozzi, Margherita Bodini, Francesco Nieddu, Silvia Ricci, Thembile Mzolo, Marco Costantini, Chiara Azzari, Michele Pellegrini
Format: Article
Language:English
Published: Taylor & Francis Group 2021-05-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
hypervirulent menc strains
cc11/cc334 clonal complexes
outbreak
menacwy-crm conjugate vaccine
menc-crm conjugate vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2020.1833578

Internet

http://dx.doi.org/10.1080/21645515.2020.1833578

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