Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons.

GABA is the key inhibitory neurotransmitter in the adult central nervous system, but in some circumstances can lead to a paradoxical excitation that has been causally implicated in diverse pathologies from endocrine stress responses to diseases of excitability including neuropathic pain and temporal...

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Bibliographic Details
Main Authors: Naomi Lewin, Emre Aksay, Colleen E Clancy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3470566?pdf=render