Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons.
GABA is the key inhibitory neurotransmitter in the adult central nervous system, but in some circumstances can lead to a paradoxical excitation that has been causally implicated in diverse pathologies from endocrine stress responses to diseases of excitability including neuropathic pain and temporal...
Main Authors: | Naomi Lewin, Emre Aksay, Colleen E Clancy |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3470566?pdf=render |
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