Hyperexcitability of Sensory Neurons in Fragile X Mouse Model

Hyperexcitability of Sensory Neurons in Fragile X Mouse Model

Sensory hypersensitivity and somatosensory deficits represent the core symptoms of Fragile X syndrome (FXS). These alterations are believed to arise from changes in cortical sensory processing, while potential deficits in the function of peripheral sensory neurons residing in dorsal root ganglia rem...

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Bibliographic Details
Main Authors: Pan-Yue Deng, Oshri Avraham, Valeria Cavalli, Vitaly A. Klyachko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
hyperexcitability
Fragile X syndrome
action potential
sensory neuron
HCN channel
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.796053/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2021.796053/full

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