Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production.

Nanomaterials may be contaminated with bacterial endotoxin during production and handling, which may confound toxicological testing of these materials, not least when assessing for immunotoxicity. In the present study, we evaluated the conventional Limulus amebocyte lysate (LAL) assay for endotoxin...

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Detalhes bibliográficos
Main Authors: Sourav P Mukherjee, Neus Lozano, Melanie Kucki, Antonio E Del Rio-Castillo, Leon Newman, Ester Vázquez, Kostas Kostarelos, Peter Wick, Bengt Fadeel
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2016-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5120825?pdf=render