Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation

Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation

Gastrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while large scale cell movements occur across the entire embryo. In amniote (reptiles, birds, mammals) embryos, the deep layers arise by epithelial-to-mesenchymal transition (EMT) at a morphologically st...

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Bibliographic Details
Main Authors: Octavian Voiculescu, Lawrence Bodenstein, I-Jun Lau, Claudio D Stern
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-05-01
Series:eLife
Subjects:
epithelial-mesenchymal interaction
EMT
cell movement
primitive streak
modelling
computer simulation
Online Access:https://elifesciences.org/articles/01817

Internet

https://elifesciences.org/articles/01817

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