Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

Alzheimer’s disease (AD) is the most common cause of progressive dementia in the elderly. It is characterized by a progressive and irreversible loss of cognitive abilities and formation of senile plaques, composed mainly of amyloid β (Aβ), and neurofibrillary tangles (NFTs), composed of tau protein,...

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Bibliographic Details
Main Authors: Md. Sahab Uddin, Anna Stachowiak, Abdullah Al Mamun, Nikolay T. Tzvetkov, Shinya Takeda, Atanas G. Atanasov, Leandro B. Bergantin, Mohamed M. Abdel-Daim, Adrian M. Stankiewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00004/full