Targeted Delivery of 111In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody

Targeted Delivery of 111In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody

Since cell nucleus is one of the most vulnerable compartments, the maximum therapeutic effect from a variety of locally acting agents, such as photosensitizers, alfa-emitters, Auger electron emitters, will be expected when they get there. Therefore, the targeted delivery of these agents into the nuc...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Tatiana S. Karyagina, Alexey V. Ulasov, Tatiana A. Slastnikova, Andrey A. Rosenkranz, Tatiana N. Lupanova, Yuri V. Khramtsov, Georgii P. Georgiev, Alexander S. Sobolev
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Frontiers Media S.A. 2020-03-01
Σειρά:Frontiers in Pharmacology
Θέματα:
affibody
cancer
epidermal growth factor receptors
modular nanotransporters
nuclear targeting
targeted drug delivery
Διαθέσιμο Online:https://www.frontiersin.org/article/10.3389/fphar.2020.00176/full

Διαδίκτυο

https://www.frontiersin.org/article/10.3389/fphar.2020.00176/full

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