A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy

A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy

Introduction: Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults and is characterized by detectable autoantibodies against glomerular antigens, most commonly phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type-1 domain containing 7A (THSD7A). In Europeans, gene...

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Bibliographic Details
Main Authors: Sanjana Gupta, Mallory Louise Downie, Chris Cheshire, Stephanie Dufek-Kamperis, Adam Paul Levine, Paul Brenchley, Elion Hoxha, Rolf Stahl, Neil Ashman, Ruth Jennifer Pepper, Sean Mason, Jill Norman, Detlef Bockenhauer, Horia Constantin Stanescu, Robert Kleta, Daniel Philip Gale
Format: Article
Language:English
Published: Karger Publishers 2023-03-01
Series:Glomerular Diseases
Subjects:
phospholipase a2 receptor 1
thrombospondin type-1 domain containing 7a
autoantibody
genetic risk score
membranous nephropathy
Online Access:https://www.karger.com/Article/FullText/529959

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https://www.karger.com/Article/FullText/529959

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