Next-Generation Sequencing of Cell-Free DNA Extracted From Pleural Effusion Supernatant: Applications and Challenges

Next-Generation Sequencing of Cell-Free DNA Extracted From Pleural Effusion Supernatant: Applications and Challenges

Cell-free DNA (cfDNA) extracted from diverse specimen types has emerged as a high quality substrate for molecular tumor profiling. Analytical and pre-analytical challenges in the utilization of cfDNA extracted from pleural effusion supernatant (PES) are herein characterized in patients with metastat...

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Bibliographic Details
Main Authors: Ami Patel, Erika Hissong, Lucelina Rosado, Robert Burkhardt, Lin Cong, Susan A. Alperstein, Momin T. Siddiqui, Hyeon Jin Park, Wei Song, Priya D. Velu, Hanna Rennert, Jonas J. Heymann
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
next generation sequencing
pleural effusion
effusion supernatant
cell-free DNA
lung adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.662312/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.662312/full

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