Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A meta-analysis.

<h4>Introduction</h4>Cystic fibrosis (CF) is a hereditary autosomal recessive disorder caused by a range of mutations in the CF Transmembrane Conductance Regulator (CFTR) gene. This gene encodes the CFTR protein, which acts as a chloride channel activated by cyclic AMP (cAMP). This meta-...

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Bibliographic Details
Main Authors: Toqa Darwish, Azhar Al-Khulaifi, Menatalla Ali, Rana Mowafy, Abdelilah Arredouani, Suhail A Doi, Mohamed M Emara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0272091